The Best Homemade Bison Lasagna Recipe

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This is the Best Homemade Bison Lasagna recipe. It’s made with homemade lasagna noodles, a flavorful ground bison meat sauce, layered with ricotta, shredded cheese, and pickled jalapeños, topped with a mix of white cheddar and pepper jack cheeses. It’s flavorful, so cheesy, and simply a recipe that you will want to make over and over again, served with Strawberry Green Tea Lemonade.

Close up on a slice of beef lasagna.

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Why This Recipe is So Good

This bison lasagna recipe is made by layering a flavorful ground bison meat sauce with ricotta cheese, 2 kinds of shredded cheese, tender lasagna noodles, and pickled jalapeños. Finished off with extra cheese, this is the best homemade lasagna recipe.

Ground bison is used for this lasagna recipe because it’s a delicious, lean ground meat that still gives this dish a hearty, meaty flavor. I find that bison tastes very similar to ground beef, just leaner. You can swap it out for ground beef if you prefer. Use lean ground beef, like 85/15 or 90/10, for a similar fat content to bison.

Everyone loves it and there are rarely any leftovers. It is the ultimate comfort dinner. This recipe makes 8 – 12 servings, but everyone always gets a second serving! Serve alongside a salad using this homemade Caesar salad recipe without anchovies.

Homemade Bison Lasagna Ingredients

All ingredients, measurements, and instructions are in the recipe card at the bottom of this post.

homemade lasagna ingredients on a counter.
  • Meat sauce. This lasagna recipe starts by making the perfect meat sauce, which includes: Ground beef or bison (they taste pretty much the same, but I prefer ground bison), cooked in rich and flavorful tomato sauce filled with chopped green bell peppers, and lots of herbs and spices
  • Three cheeses. You will need three kinds of cheese for maximum deliciousness: Ricotta cheese, White cheddar cheese, pepper jack cheese. The mix of the white cheddar and pepper jack cheeses throughout the lasagna, adds flavor and a hint of spice.
  • Chopped jalapeños. Chopped pickled jalapeños are included in between the layers of the lasagna. They are not very spicy at all. They help to add a slight spice and tangy flavor to the lasagna. 
  • Homemade Lasagna Noodles. I used a homemade lasagna noodles recipe included in the recipe card. You can use either a pasta roller(quicker and easier option) or a rolling pin(yields slightly thicker noodles). Feel free to use store-bought lasagna noodles instead.

How To Make Homemade Ground Bison Lasagna

Overhead view of homemade lasagna ingredients on a table.

Boil lasagna noodles

Cook the lasagna noodles according to package instructions. Rub each sheet of pasta with olive oil so keep them from sticking to each other then cover with plastic wrap so the pasta doesn’t dry out.

If you are making the pasta from scratch, the recipe is located in the recipe card notes below.

Make the meat sauce

Heat olive oil in a large skillet over medium heat. Cook the onions and bell pepper for 3 – 5 minutes, or until they just start to brown. Add the ground bison and spices, stirring until combined, then allow the meat to brown, about 10 minutes.

Add in tomato paste, allow to cook for 1 minute to get rid of the bitter canned tomato flavor, then stir in the tomato sauce and bay leaves. Allow the sauce to simmer on medium-low heat for another 15 – 20 minutes to allow all the flavors to meld together.

Layer lasagna

How to layer lasagna. Process image of lasagna being layered before baking.

To the bottom of a 9×13-inch baking dish add 3/4 cup of the meat sauce, spreading it out evenly. Layer a sheet of lasagna noodles, ricotta cheese, shredded cheese, another layer of noodles, meat sauce, and pickled jalapeños. Repeat until you have used up all the ingredients. Top the lasagna with the rest of the shredded cheese.

Bake and serve lasagna

Bake uncovered until the cheese is browned and bubbly. Allow your bison lasagna to cool for 10 minutes, then serve garnished with fresh parsley or fresh basil.

Baked homemade lasagna with homemade noodles on a plate.
traditional lasagna recipe easy

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The Best Homemade Lasagna Recipe

This is the Best Homemade Bison Lasagna recipe. It's made with homemade lasagna noodles, a flavorful ground bison meat sauce, layered with ricotta, shredded cheese, and pickled jalapeños, topped with a mix of white cheddar and pepper jack cheeses. It's flavorful, so cheesy, and simply a recipe that you will want to make over and over again, served with Strawberry Green Tea Lemonade.
Prep Time50 minutes
Cook Time1 hour 20 minutes
Total Time2 hours 10 minutes
Course: Dinner, Main Dish
Cuisine: American, Italian
servings8 servings
Calories: 1521kcal
Author: Tonya Fowler
Cost: $20

Equipment

Ingredients

Lasagna noodles

  • 1 lb store-bought lasagna noodles or 10 sheets of homemade lasagna noodles homemade pasta recipe is in the recipe notes below

Meat sauce

  • 4 tablespoons olive oil
  • 1 small yellow onion chopped
  • 1 medium green bell pepper chopped
  • 1 ½ lb ground bison or ground beef
  • 2 teaspoons salt
  • 1 teaspoon ground black pepper
  • 1 ½ teaspoon dried thyme
  • ¾ teaspoon dried rosemary
  • ½ teaspoon red crushed pepper flakes
  • 1 ¼ teaspoon garlic powder
  • ¾ teaspoon onion powder
  • 1(6) ounce can of tomato paste
  • 2(15) ounce cans of tomato sauce
  • 3 bay leaves

Cheeses

  • 1(15) ounce container of ricotta cheese
  • 16 ounces shredded cheese pepper jack cheese and white cheddar cheese, 5 cups

Optional

  • 4 ounces pickled jalapeños roughly chopped, optional
  • Fresh parsley or basil for garnish
  • Side salad

Instructions

Boil lasagna noodles

  • Start by boiling lasagna noodles according to the package instructions. After boiling, rub each piece with olive oil to prevent sticking, then cover to keep it from drying out.
    If you are making lasagna noodles from scratch, the homemade recipe is in the recipe card notes below.
    1 lb store-bought lasagna noodles or 10 sheets of homemade lasagna noodles

Making the meat sauce

  • Heat olive oil in a large skillet over medium heat. Cook the onions and bell pepper for 3 – 5 minutes, or until they just start to brown. Add the ground bison and spices, stirring until combined, then allow the meat to brown, about 10 minutes.
    4 tablespoons olive oil, 1 small yellow onion, 1 medium green bell pepper, 1 ½ lb ground bison, 2 teaspoons salt, 1 teaspoon ground black pepper, 1 ½ teaspoon dried thyme, ¾ teaspoon dried rosemary, ½ teaspoon red crushed pepper flakes, 1 ¼ teaspoon garlic powder, ¾ teaspoon onion powder
  • Add in tomato paste, allow to cook for 1 minute to get rid of the bitter canned tomato flavor, then stir in the tomato sauce and bay leaves. Allow the sauce to simmer on medium-low heat for another 15 – 20 minutes to allow all the flavors to meld together. Discard bay leaves once the meat sauce is finished cooking.
    1(6) ounce can of tomato paste, 2(15) ounce cans of tomato sauce, 3 bay leaves

How to Layer the Lasagna and Baking

  • Preheat your oven to 400 degrees Fahrenheit. In a 9 x 13-inch baking dish, add ¾ cup of the meat sauce on the bottom, a layer of noodles, ¼ cup of ricotta cheese, and ½ cup of shredded cheese. Cover with noodles, more sauce, and some of the pickled jalapeños if using. 
    1(15) ounce container of ricotta cheese, 16 ounces shredded cheese, 4 ounces pickled jalapeños
  • Repeat alternating the ricotta and shredded cheese layer with the meat sauce layers until you have used up all the ingredients, ending with the meat sauce. You will have 7 layers. Lastly, cover the top with the rest of the shredded cheese.
  • Bake for 45 minutes at 400 degrees Fahrenheit, or until the cheese is brown and bubbly.
  • Allow the lasagna to cool for 10 minutes then garnish with fresh parsley or freshly torn basil. Serve with a side salad and enjoy!

Notes

*Use 1lb of lasagna noodles instead. Boil the noodles according to the package instructions. After boiling rub with olive oil to keep them from sticking to each other, and then set aside covered with plastic wrap or a lid so they don’t dry out.

Make the homemade lasagna noodles

  • 2 cups all-purpose flour
  • ¼ cup semolina flour (important to use; otherwise lasagna noodles will be too soft)
  • 1 ½ teaspoons salt
  • 3 large eggs
  • 3 tablespoons water
In a large mixing bowl, mix together all-purpose flour, semolina flour, and salt. Use a fork to mix in the eggs until well incorporated. You should have large crumbles.
Transfer mixture to a food processor, then pulse until you have small crumbles. Add the water in 1 tablespoon at a time until the pasta dough starts to stick together and forms large clumps. Turn the dough out onto a clean counter, then knead a couple of times to form a ball. The dough will be very stiff. Wrap the dough in plastic wrap, then allow it to rest in a warm environment for 30 minutes. It will soften as it rests.
Roll out pasta dough and boil
Divide the dough into 4 pieces, work with one piece at a time, keeping the rest of the dough covered so it doesn’t dry out. Dust the pasta dough with flour, then use a rolling pin to roll out the dough into a rectangle about 1/4 inch thick. Then generously dust a pasta roller with flour, and roll out the pasta on the largest setting. Continue running the dough through the machine, each time lowering the setting until you reach the second smallest setting. Cut the dough into 12-inch pieces, lengthwise. Repeat with the remaining balls of dough.
Boil a large pot of water. Cook two lasagna noodles at a time, making sure they don’t fold over each other. Boil for 1 minute, then place the pasta onto a greased cookie sheet. Oil each layer of the pasta noodles so they don’t stick to each other. Set aside covered until you are ready to assemble the lasagna. Yields 10 lasagna noodles

Nutrition

Calories: 1521kcal | Carbohydrates: 111g | Protein: 95g | Fat: 82g | Saturated Fat: 45g | Polyunsaturated Fat: 4g | Monounsaturated Fat: 26g | Cholesterol: 299mg | Sodium: 5642mg | Potassium: 3803mg | Fiber: 17g | Sugar: 39g | Vitamin A: 6705IU | Vitamin C: 80mg | Calcium: 1293mg | Iron: 15mg

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